RjHan:SD rat Fmr1


Available to order

International strain nameRjHan:SD rat Fmr1
Alternative nameFmr1
Strain typeEndonuclease-mediated
Allele/Transgene symbolZygote electroporation of gene-specific gRNA and Cas9 was used to ablate specific sequence corresponding to the exon3.
Gene/Transgene symbolFmr1

Information from provider

ProviderJana Kopkanova
Provider affiliationTransgenic and Archiving Module, Institute of Molecular Genetics of the Czech Academy of Sciences
Genetic informationFMRP translational regulator 1 (FMRP) gene - Mutant rats were generated by zygote electroporation of gene-specific gRNAs (5´-GCAAGAATTGACTACCTCGT-3´ and 5´-GGGGCAAGGGTCTACTAATG-3´) and Cas9 was used to ablate specific sequence corresponding to the exon 3. Such a genomic deletion results in a presumably non-functional protein variant (i.e. gene knock-out)
Phenotypic informationHomozygous:
not analyzed

not analyzed
Breeding history2 crossings to RjHan:SD rats
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic
Animals used for archivingwild-type rat Sprague-Dawley , heterozygous rat Sprague-Dawley
Stage of embryos2-cell

Information on how we integrate external resources can be found here



Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Other EMMA strains

Not found what you were looking for? Search here for other strains available from EMMA.

INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).