STOCK Il10tm1a(EUCOMM)Wtsi/Cnbc


Available to order

International strain nameSTOCK Il10tm1a(EUCOMM)Wtsi/Cnbc
Alternative nameSTOCK.Il10/Cnbc
Strain typeTargeted Mutant Strains
Allele/Transgene symbolIl10tm1a(EUCOMM)Wtsi,
Gene/Transgene symbolIl10

Information from provider

ProviderAurora Pujol
Provider affiliationNeurosciences. Neurometabolic Diseases, IDIBELL
Genetic informationHeterozygous mice, carrying a genetically modified tm1a allele of the Il10 gene (produced by EUCOMM; ES cell clone EPD0158_4_D06), were produced at CNB-CSIC, under Infrafrontier-I3 project (WP8 work-package). GLT chimera bred to albino outbred mice. Resulting animals further bred to CD1 for archiving purposes, resulting in a STOCK (albino outbred) genetic background.
Phenotypic informationHomozygous:
None, unless the gene is deleted via cre-loxP strategies.

Breeding historyES cells from C57BL/6N genetic background resulting in a GLT chimera bred to albino outbred animals. Resulting animals bred to CD1 albino outbred mice for archiving purposes. Mixed background.
ReferencesNone available
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreCNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain
Animals used for archivingheterozygous mixed

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

    • Immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections syndrome / Orphanet_238569

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Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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