Available to order

International strain nameC57BL/6N-Il10tm1a(EUCOMM)Wtsi/Cnbc
Alternative nameB6N.Il10/Cnbc
Strain typeTargeted Mutant Strains
Allele/Transgene symbolIl10tm1a(EUCOMM)Wtsi,
Gene/Transgene symbolIl10

Information from provider

ProviderAurora Pujol
Provider affiliationNeurosciences. Neurometabolic Diseases, IDIBELL
Genetic informationHeterozygous mice, carrying a genetically modified tm1a allele of the Il10 gene (produced by EUCOMM; ES cell clone EPD0158_4_D06), were produced at CNB-CSIC, under Infrafrontier-I3 project (WP8 work-package). GLT chimera bred to C57BL/6N mice. Resulting animals further bred to C57BL/6N for archiving purposes.
Phenotypic informationHomozygous:

Breeding historyES cells from C57BL/6N genetic background resulting in a GLT chimera bred to C57BL/6N mice. Resulting animals bred to C57BL/6N mice for archiving purposes. C57BL/6N background.
ReferencesNone available
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreCNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain
Animals used for archivingheterozygous C57BL/6N

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

    • Immune dysregulation-inflammatory bowel disease-arthritis-recurrent infections syndrome / Orphanet_238569

Information on how we integrate external resources can be found here



Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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